Pharmafile Logo
  • - PMLiVE
  • - PMLiVE
  • Diversity, Equity and Inclusion
  • Communiqué 53 Cover Image

Abstract Highlights from EHA 2022 : A Spotlight on Lymphoma

July 26, 2022 | CME, Medscape Oncology, medical education 

- PMLiVE

Spotlight on Lymphoma

Ahead of EHA 2022, Medscape Education Chief Medical Officer, Hansa Bhargava, MD, caught up with Dr Loretta Nastoupil, US, on the most important abstracts to look out for in lymphoma. Here are some of the highlights…

  1. Update on the ECHELON-1 study in frontline Hodgkin lymphoma, where an OS advantage was seen when bleomycin was replaced with brentuximab vedotin in frontline, ABVD, which is potentially practice-changing.
  2. The results of the Ph 3 SHINE study have been eagerly awaited for many years in untreated mantle cell lymphoma, and showed a significant improvement in PFS with ibrutinib + bendamustine + rituximab and rituximab maintenance vs standard chemoimmunotherapy.
  3. Positive Ph 2 efficacy data with the bispecific antibodies, glofitamab for relapsed/refractory (R/R) diffuse large B-cell lymphoma, and mosunetuzumab for R/R follicular lymphoma, building on the Ph 1 data previously reported.
  4. Other CAR T-cell therapies with novel targets and in other indications are emerging, such as for T-cell lymphoma where there is a high unmet need for new therapies. Some manipulations to manufacturing also result in an auto CAR within 2 days. So, while CAR T-cell therapy is not new, there are new implementations of therapy that have been around for several years.
  5. Important to now learn regarding patient selection, sequencing CD19 directed therapy and how to account for the patient experience for which there will also be more PRO data reported.

You can also watch the full video here

About Medscape:
Medscape delivers dynamic, innovative education to optimize learner engagement and patient outcomes worldwide. Medscape is the leading online global destination for physicians and healthcare professionals, providing over 5 million members with the latest medical news, expert opinion, and precision education (CME and CPD) to improve clinical practice and advance health outcomes. Medscape’s unrivalled membership reach and therapeutic expertise deliver education across 30+ specialties in 40+ learning formats, using the latest digital and live technology.

This content was provided by Medscape Education

Company Details

Medscape Logo

Medscape Education

Email
Website

 Latest Content from  Medscape Education 

Breakthrough Alzheimer’s Therapies Drive Early Detection Rates While Exposing Deep Treatment Disparities

Analysis from Komodo Health and Medscape Education shows cognitive screening up 10% and biomarker testing up 23%, yet significant disparities persist in detection for women and treatment access for Black...

Virtual Practice, Real Results: The Power of Virtual Patient Simulation

Simulation has never been more vital in medicine than it is today. As increasing numbers of physicians turn to large language models for clinical answers1, the real differentiator isn’t just...

A New Destination for Oncology Education

Medscape Oncology is pleased to announce the launch of a groundbreaking new learning space designed to provide education across tumor types and oncology disciplines: PIONEER – PrecIsion Oncology: Navigating EvidEnce...

A Call to Action: Bridging the Adult Immunization Divide

Over the past few years, as new diseases have emerged or reemerged, a host of new vaccines have become available while many others are in the pipeline. For older adults,...

Medscape Education Returns as Thought Leaders to AIS 2025

📍 September 8–10, 2025 Hilton at Penn’s Landing | Philadelphia, PA Medscape Education is proud to return to the 2025 Alliance Industry Summit (AIS) as a Silver Sponsor and leading...

What Do Pickleball and Medscape Education Have in Common? Heather Lavigne.

When she’s not taking on challengers on the pickleball court, you can find Heather Lavigne leading Medscape Education’s dynamic insights and impact team as Senior Director. Her leadership philosophy is...

Medscape Education: Celebrating the Power, Purpose, and Future of Women in Medicine

Medscape Education is proud to return to the Power of Women in Medicine Summit™, reaffirming its commitment to uplifting, empowering, and amplifying women across healthcare. As a sponsor, Medscape brings...

Medscape Cardiology: Leading the Future of Heart Failure Education at HFSA 2025

Medscape Cardiology | theheart.org is proud to be at the forefront of the Heart Failure Society of America (HFSA) Annual Scientific Meeting (ASM), September 26–29, 2025, in Minneapolis, MN! With...

Medical Misinformation and Sensationalism in the Age of Social Media

In today’s digital age, misinformation spreads faster than ever, often driven by sensational headlines and influencer content. These sources of misinformation often overshadow evidence-based content, creating confusion for both healthcare...

Medscape To Bring Leading Cardiology Education to ESC

The Medscape Global team is bringing their leading cardiology education and proven impact to the European Society of Cardiology (ESC) Congress in Madrid for 2025. Powered by enhanced technologies, methodologies,...