Pharmafile Logo

Shifting the Paradigm: A New Era for Parkinson’s Care

In this episode of “Hear From Her:” Hear from two leaders at the forefront of a much-needed change in how Parkinson’s is understood, diagnosed, and treated.

- PMLiVE

Padma Mahant, MD, was working in a clinic as a movement disorder specialist when she noticed a disturbing trend. Patients eventually diagnosed with Parkinson’s disease “took several years to find their way to me,” she says. There were many misdiagnoses and multiple medication trials before finally getting correctly diagnosed.  And during that elapsed time, their Parkinson’s had progressed quite a bit. “It seemed like such a lost opportunity for early intervention,” Mahant says, “because we know from studies that starting treatment early can improve quality of life and slow the disease’s progression significantly.”

That realization was a turning point in Mahant’s career. She decided she wanted to become involved in educating clinicians about Parkinson’s symptoms during the “significant prodromal state prior to developing motor symptoms” and researching and creating a diagnostic tool for clinicians to use.

Mahant still sees patients, but now she’s also Director of Medical Affairs at CND Life Sciences, a company leading the way in advancing the care of patients facing a potential diagnosis of a neurodegenerative disease. And they have made breakthroughs: CND recently presented a sleep study that revealed a particular protein detected in 75% of Parkinson’s patients with Rapid Eye Movement Sleep Behavior Disorder but no motor symptoms. Manant says she believes “this is an opportunity to really move the needle” in terms of early intervention and towards disease modification.

Before her big career pivot, Mahant says, “one of the first people I called to say, ‘Hey, I’m thinking about making this shift and what do you think?’ Was Indu.”

Indu is Dr. Indu Subramanian, clinical professor of neurology at UCLA and director of the South West Parkinson Disease Research, Education and Clinical Care Center of Excellence. She is also board certified in Integrative medicine and co-chair of the Wellness Task Force at the Movement Disorders Society.  “As a young neurologist, I found that classic Western medicine wasn’t really serving my patients that well. So I became curious about other things,” she says.

Subramanian started her own yoga and mindfulness practices and ended up training to teach both. She also became interested in integrative medicine and alternative practices like Ayurveda and traditional Chinese medicine, and started really leaning into those things for her Parkinson’s patients, to help with the emotional distress that Parkinson’s can cause.

The image most people have of Parkinson’s, Subramanian says, is an older Caucasian man with a tremor. However, a growing body of evidence, and the stories of countless patients, challenges this outdated view.  Changing the Parkinson’s narrative, especially for women, requires not just better science, but also raising awareness about prodromal symptoms and the need for clinicians to be more proactive about early diagnosing. 

Women in a prodromal stage, for instance, often experience anxiety and constipation, but are often told their symptoms are stress-related.  Once patients understand that they are experiencing Parkinson’s type symptoms, we can teach them wellness strategies and lifestyle changes to help them live better, they say.  “Hopefully, developing those strategies early can help prevent progression.”

“I think we all went into medicine to help make other people’s lives better,” says Subramanian. “What fills my teacup time and time again is helping a patient and hearing that they’re doing better because of something that I was able to bring, uniquely as a woman perhaps. Who was able to slow down and take the time and connect, offer them something to help them feel better other than a pill or surgery.”

Hosted by Sara Thorpe, Director of Clinical Strategy at Medscape Education

Follow us for updates on upcoming podcasts and more insightful conversations.

For more information, please contact Jelena Spyropoulos.

About Medscape Education

Medscape Education (medscape.org) is the leading destination for continuous professional development, consisting of more than 30 specialty-focused destinations offering thousands of free CME and CE courses for physicians, nurses, and other healthcare professionals.

This content was provided by Medscape Education

Company Details

 Latest Content from  Medscape Education 

“CGM Sweet Talk With the Sugar Queens” Takes Silver at the 2025 Digital Health Awards

Medscape Education’s dynamic educational series, CGM Sweet Talk With the Sugar Queens, has earned a Silver Award in the Video Series (Digital Health Media / Publications) category at the 2025...

Medscape at ASH 2025: Landmark Value Through the Medscape AI Debut and Five Educational Symposia

For decades, Medscape has been the brand physicians trust. Now, Medscape is forging a new path into the future at ASH 2025 with the launch of Medscape AI — the...

Women Leaders Rewriting the Protocols of Rare Disease Care

The true measure of a medical leader is the courage to act when existing systems fail the patient. This is the professional and personal ethos of clinical immunologist Dr. Hilary...

The Power of the Pivot: How Nurse Practitioners are Closing Care Gaps for Women

The career path of a Nurse Practitioner is often envisioned as a straight line: clinical practice, specialization, perhaps a supervisory role. But for two pioneering NPs, Laura Demuth and Jackie...

Voices of Change: Women Leading the Menopause Movement

For decades, menopause has been swept under the rug, or into the dark corners of clinicians’ offices, often dismissed as something women just had to “get past” and hardly worth...

Medscape Wins Anthem Award for Rare Disease Education Platform

Platform has reached 2.4 million healthcare professionals worldwide since 2021. Newark, NJ - [November 18, 2025] - Medscape, the leading digital platform for physicians and healthcare professionals (HCPs), has been...

Shifting the Paradigm: A New Era for Parkinson’s Care

In this episode of “Hear From Her:” Hear from two leaders at the forefront of a much-needed change in how Parkinson’s is understood, diagnosed, and treated.

World Orphan Drug Congress 2025 in Amsterdam

Medscape Education will make its debut at the World Orphan Drug Congress (WODC) 2025, taking place in Amsterdam, the Netherlands, October 28-29.

Medscape Education: Pioneering Pathways at ESMO 2025

Medscape Oncology will be pioneering pathways at the 2025 ESMO congress taking place in Berlin, Germany this October.

Game On: Medscape Education Golfs for a Cause

Medscape Education is proud to stand alongside the National Kidney Foundation (NKF) as a sponsor of one of the nation’s most impactful charity events benefiting patients living with kidney disease,...