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elotuzumab

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NHS England pledges to streamline clinical trial setup

The process will also target the procedure for reimbursements in additional treatment costs

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Daily Brief: Deal done, Takeda to cut $1.4bn, Brexit latest, Valeant rebrands

A rapid round-up of the top pharma, biotech and healthcare news

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FDA clears first-line use for J&J’s Darzalex

Front-line approval a milestone for blockbuster-tipped myeloma drug

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Amgen and Novartis migraine drug hits the mark again

Aimovig will become the first CGRP receptor-targeting drug if it reaches market

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Merck’s Keytruda scores in frontline lung cancer yet again

Drug improved overall survival as a monotherapy, which rival BMS’ Opdivo was unable to show

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Incyte/Merck trial failure bodes ill for IDO class

The much-touted cancer immunotherapy combination fails to show improvement over Keytruda alone

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ViiV’s two-drug HIV combo backed by CHMP

The committee also backs two biosimilar medicines

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IMI calls for advancements in machine learning and digital clinical trials

Will reserve up to €82m for universities, SMEs and patient organisations

Sanofi reception

Sanofi, Regeneron offer price cut for cholesterol drug Praluent

Amgen’s Repatha also struggled to secure reimbursement at its launch price point

AstraZeneca AZ

AZ pushes back data read-out from MYSTIC lung cancer trial

The delay could further undermine confidence in a positive outcome

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Novartis pushes ‘virtual’ clinical trial concept

Teams up with Science 37 to run ten digital-based trials over the next three years

translational pharmacology medicine dose

UK government updates the Model Clinical Trials Agreement

New regulation aims to speed-up R&D

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