| Company Name | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024(F) | 2025(F) | 2026(F) | 2027(F) | 2028(F) | 2029(F) | 2030(F) | 2023 Growth($M) | 2023 Growth(%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neurocrine Biosciences Inc | - | - | - | - | - | - | - | - | - | - | - | $116 | $410 | $753 | $994 | $1,090 | $1,441 | $1,836 | $2,290 | $2,798 | $3,418 | $3,899 | $4,475 | $4,928 | $5,508 | $395 | 27.4% |
| Grunenthal GmbH | - | - | - | - | - | - | - | - | - | - | - | $327 | $916 | $872 | $868 | $945 | $945 | $934 | - | - | - | - | - | - | - | ($11) | -1.2% |
| H. Lundbeck AS | $1,155 | $1,564 | $1,872 | $2,052 | $2,219 | $2,538 | $2,135 | $2,176 | $1,989 | $1,661 | $1,742 | $1,948 | $2,085 | $1,769 | $1,818 | $2,116 | $2,289 | $2,352 | $2,680 | $2,839 | $2,968 | $2,908 | $2,945 | $2,782 | $2,562 | $63 | 2.8% |
| Eisai Co Ltd | $2,490 | $2,823 | $3,499 | $3,774 | $3,604 | $2,481 | $1,905 | $1,782 | $1,597 | $1,446 | $1,451 | $1,488 | $1,525 | $1,617 | $1,489 | $1,091 | $967 | $1,005 | $1,278 | $1,952 | $2,878 | $3,979 | $5,138 | $4,670 | $5,295 | $38 | 3.9% |
| Jazz Pharmaceuticals Plc | $29 | $39 | $54 | $97 | $143 | $233 | $405 | $596 | $805 | $981 | $1,137 | $1,214 | $1,426 | $1,647 | $1,785 | $2,336 | $2,760 | $2,708 | $2,666 | $2,799 | $2,956 | $2,928 | $3,260 | $3,436 | $3,659 | ($52) | -1.9% |
| Otsuka Holdings Co Ltd | $1,878 | $2,322 | $2,995 | $3,850 | $4,245 | $5,028 | $5,489 | $6,377 | $6,755 | $3,706 | $2,264 | $2,319 | $2,591 | $2,904 | $3,158 | $2,820 | $3,024 | $3,381 | $3,868 | $3,902 | $3,909 | $3,989 | $4,176 | $3,782 | $3,012 | $357 | 11.8% |
| Viatris Inc | - | $28 | $219 | $238 | $343 | $477 | $741 | $850 | $1,018 | $1,011 | - | - | - | - | - | $2,394 | $2,104 | $1,971 | - | - | - | - | - | - | - | ($133) | -6.3% |
| Teva Pharmaceutical Industries Ltd | $1,458 | $1,833 | $2,437 | $2,665 | $3,202 | $4,296 | $5,090 | $5,110 | $5,053 | $4,780 | $4,833 | $4,056 | $2,573 | $2,020 | $2,138 | $2,070 | $1,996 | $2,249 | $2,575 | $2,869 | $3,227 | $3,555 | $3,865 | $4,136 | $4,408 | $253 | 12.7% |
| Eli Lilly and Co | $6,574 | $7,433 | $8,347 | $8,954 | $9,377 | $9,671 | $7,533 | $7,163 | $3,561 | $2,907 | $2,693 | $2,124 | $1,794 | $1,702 | $1,682 | $1,763 | $1,421 | $2,651 | $1,157 | $1,492 | $2,064 | $2,919 | $3,617 | $4,438 | $5,150 | $1,230 | 86.6% |
| Takeda Pharmaceutical Co Ltd | - | $1 | $1 | $1 | $17 | $63 | $157 | $199 | $331 | $400 | $530 | $688 | $1,346 | $3,822 | $3,750 | $4,105 | $4,529 | $4,176 | $2,908 | $2,063 | $1,607 | $1,320 | $1,308 | $1,435 | $1,645 | ($353) | -7.8% |
| Pfizer Inc | $9,277 | $9,623 | $10,928 | $11,341 | $13,286 | $13,153 | $12,750 | $12,929 | $12,548 | $10,196 | $10,410 | $9,637 | $8,628 | $6,806 | $1,350 | $762 | $221 | $928 | $1,359 | $1,649 | $1,911 | $2,156 | $2,396 | $2,609 | $2,798 | $707 | 319.9% |
| Novartis AG | $2,306 | $2,532 | $2,540 | $2,676 | $2,814 | $3,506 | $4,115 | $4,719 | $5,137 | $4,163 | $3,835 | $3,802 | $3,341 | $3,713 | $4,272 | $5,006 | $5,050 | $4,968 | $6,036 | $6,672 | $7,288 | $7,872 | $8,369 | $8,831 | $9,286 | ($82) | -1.6% |
| Sanofi | $4,245 | $3,758 | $2,618 | $2,318 | $2,272 | $1,828 | $1,206 | $1,471 | $1,763 | $2,217 | $2,814 | $3,092 | $3,224 | $3,196 | $2,460 | $2,409 | $2,220 | $1,033 | $438 | $386 | $496 | $702 | $931 | $1,206 | $1,518 | ($1,187) | -53.5% |
| Johnson & Johnson | $8,303 | $9,873 | $9,316 | $6,497 | $5,056 | $5,347 | $3,844 | $3,931 | $4,017 | $4,194 | $4,281 | $4,165 | $4,328 | $4,714 | $4,917 | $5,505 | $5,643 | $5,587 | $6,399 | $6,824 | $7,342 | $7,795 | $8,136 | $8,495 | $8,842 | ($56) | -1.0% |
| AbbVie Inc | - | - | - | - | - | $125 | $149 | $746 | $770 | $705 | $721 | $765 | $821 | $809 | $1,570 | $2,791 | $3,334 | $4,450 | $5,625 | $6,784 | $7,849 | $8,967 | $10,015 | $10,124 | $9,161 | $1,116 | 33.5% |
| Merck & Co Inc | $671 | $796 | $906 | $933 | $1,274 | $1,511 | $1,584 | $1,127 | $1,052 | $824 | $932 | $1,277 | $1,512 | $1,886 | $1,924 | $1,850 | $1,943 | $2,073 | $1,955 | $1,977 | $1,404 | $1,007 | $840 | $662 | $523 | $130 | 6.7% |
| Roche Holding AG | - | - | $288 | $262 | $296 | $332 | $331 | $338 | $319 | $286 | $294 | $1,222 | $2,754 | $4,102 | $5,072 | $6,738 | $8,094 | $9,362 | $10,191 | $10,979 | $11,689 | $12,416 | $12,999 | $13,226 | $13,529 | $1,268 | 15.7% |
| Biogen Inc | $1,742 | $2,098 | $2,792 | $3,099 | $3,418 | $3,780 | $4,106 | $5,482 | $8,007 | $8,583 | $8,836 | $9,862 | $10,319 | $10,628 | $9,884 | $8,005 | $7,230 | $6,466 | $6,305 | $5,987 | $5,803 | $5,692 | $5,586 | $5,514 | $5,496 | ($764) | -10.6% |
| UCB SA | $1,172 | $1,723 | $2,215 | $1,765 | $1,919 | $2,027 | $1,892 | $1,966 | $2,042 | $2,015 | $2,205 | $2,479 | $2,775 | $2,947 | $3,265 | $3,829 | $2,983 | $2,386 | $2,375 | $2,406 | $2,245 | $2,080 | $2,047 | $2,041 | $2,067 | ($597) | -20.0% |
| Merck KGaA | $1,815 | $1,668 | $1,957 | $2,135 | $2,224 | $2,352 | $2,433 | $2,476 | $2,443 | $1,995 | $1,926 | $1,822 | $1,803 | $1,786 | $1,895 | $1,945 | $1,833 | $1,801 | $1,781 | $1,778 | $1,720 | $1,195 | $1,036 | $978 | $914 | ($32) | -1.7% |






