Pharmafile Logo
  • - PMLiVE
  • - PMLiVE
  • Diversity, Equity and Inclusion
  • Communiqué 53 Cover Image

Abstract Highlights from EHA 2022 : A Spotlight on Lymphoma

July 26, 2022 | CME, Medscape Oncology, medical education 

- PMLiVE

Spotlight on Lymphoma

Ahead of EHA 2022, Medscape Education Chief Medical Officer, Hansa Bhargava, MD, caught up with Dr Loretta Nastoupil, US, on the most important abstracts to look out for in lymphoma. Here are some of the highlights…

  1. Update on the ECHELON-1 study in frontline Hodgkin lymphoma, where an OS advantage was seen when bleomycin was replaced with brentuximab vedotin in frontline, ABVD, which is potentially practice-changing.
  2. The results of the Ph 3 SHINE study have been eagerly awaited for many years in untreated mantle cell lymphoma, and showed a significant improvement in PFS with ibrutinib + bendamustine + rituximab and rituximab maintenance vs standard chemoimmunotherapy.
  3. Positive Ph 2 efficacy data with the bispecific antibodies, glofitamab for relapsed/refractory (R/R) diffuse large B-cell lymphoma, and mosunetuzumab for R/R follicular lymphoma, building on the Ph 1 data previously reported.
  4. Other CAR T-cell therapies with novel targets and in other indications are emerging, such as for T-cell lymphoma where there is a high unmet need for new therapies. Some manipulations to manufacturing also result in an auto CAR within 2 days. So, while CAR T-cell therapy is not new, there are new implementations of therapy that have been around for several years.
  5. Important to now learn regarding patient selection, sequencing CD19 directed therapy and how to account for the patient experience for which there will also be more PRO data reported.

You can also watch the full video here

About Medscape:
Medscape delivers dynamic, innovative education to optimize learner engagement and patient outcomes worldwide. Medscape is the leading online global destination for physicians and healthcare professionals, providing over 5 million members with the latest medical news, expert opinion, and precision education (CME and CPD) to improve clinical practice and advance health outcomes. Medscape’s unrivalled membership reach and therapeutic expertise deliver education across 30+ specialties in 40+ learning formats, using the latest digital and live technology.

This content was provided by Medscape Education

Company Details

Medscape Logo

Medscape Education

Email
Website

 Latest Content from  Medscape Education 

Shifting the Paradigm: A New Era for Parkinson’s Care

In this episode of “Hear From Her:” Hear from two leaders at the forefront of a much-needed change in how Parkinson’s is understood, diagnosed, and treated.

World Orphan Drug Congress 2025 in Amsterdam

Medscape Education will make its debut at the World Orphan Drug Congress (WODC) 2025, taking place in Amsterdam, the Netherlands, October 28-29.

Medscape Education: Pioneering Pathways at ESMO 2025

Medscape Oncology will be pioneering pathways at the 2025 ESMO congress taking place in Berlin, Germany this October.

Game On: Medscape Education Golfs for a Cause

Medscape Education is proud to stand alongside the National Kidney Foundation (NKF) as a sponsor of one of the nation’s most impactful charity events benefiting patients living with kidney disease,...

Innovation in Action at AAFP FMX 2025

This year, Medscape Education is redefining the live learning experience at AAFP FMX 2025. With 8 groundbreaking, accredited symposia, we are proud to be at the heart of the meeting,...

Shifting the Paradigm: A New Era for Parkinson’s Care

In this episode of “Hear From Her:” Hear from two leaders at the forefront of a much-needed change in how Parkinson’s is understood, diagnosed, and treated.

Global Healthy Living Foundation and Medscape Education Join Forces to Bridge the Gap Between Patients and Providers with Immunology Education

UPPER NYACK, N.Y.--(BUSINESS WIRE)--The Global Healthy Living Foundation (GHLF) today announced a new partnership with Medscape Education to advance patient-centered innovation within the Immunology Learning Nexus (Nexus), Medscape’s flagship multi-year...

Breakthrough Alzheimer’s Therapies Drive Early Detection Rates While Exposing Deep Treatment Disparities

Analysis from Komodo Health and Medscape Education shows cognitive screening up 10% and biomarker testing up 23%, yet significant disparities persist in detection for women and treatment access for Black...

Virtual Practice, Real Results: The Power of Virtual Patient Simulation

Simulation has never been more vital in medicine than it is today. As increasing numbers of physicians turn to large language models for clinical answers1, the real differentiator isn’t just...

A New Destination for Oncology Education

Medscape Oncology is pleased to announce the launch of a groundbreaking new learning space designed to provide education across tumor types and oncology disciplines: PIONEER – PrecIsion Oncology: Navigating EvidEnce...