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Early Pipeline Case Study

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Merck’s Keytruda scores in frontline lung cancer yet again

Drug improved overall survival as a monotherapy, which rival BMS’ Opdivo was unable to show

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AbbVie’s upadacitinib aces phase III trial

Arthritis drug outperformed both placebo and Humira in the study

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Boehringer builds in immuno-oncology with €1.1bn-plus OSE deal

Offers €15m upfront for the anti-SIRP-alpha antibody and €15m when it reaches phase I testing

The two ‘c’s’ of public health: confounding and causal inference*

Rerum cognoscere causas. This phrase translates as ‘to know the causes of things’. It is the basis and impetus of public health. But epidemiologists have a different word for it:...

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Incyte/Merck trial failure bodes ill for IDO class

The much-touted cancer immunotherapy combination fails to show improvement over Keytruda alone

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Novartis buys gene therapy firm AveXis for $8.7bn

Lead candidate AVXS-101 could potentially replace regular drug treatment for SMA with a one-off intervention

Segmentation, evolved

My research into the evolution of the life science industry reveals broad, sweeping trends, as I wrote about in previous PME articles such as “Selection Pressures” and “Explosive Evolution”. But...

Biogen Idec building

Settlement clears path for Biogen, Samsung’s Humira biosimilar

Agreement could see Europe access Imraldi as early as October this year

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Novo Nordisk pays $400m for EpiDestiny’s sickle cell drug

The candidate is expected to start a phase II trial in the coming months

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FTI Consulting appoints Andrew Ward

He joins the healthcare communications practice as managing director

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Reviews start for Pfizer’s wildcard lung cancer drug dacomitinib

Both EU and US regulatory advisors are currently assessing the drug

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IQVIA collaborates with MuleSoft

Will deliver integration technology to life science companies

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