
RSV affects approximately 64 million people around the world each year

Globally, five billion doses of the companies’ vaccine have been distributed

A phase 3 study showed the vaccine was 85.7% effective in those with three or more symptoms

Both boosters produced a better immune response against Omicron BA.4/BA.5 subvariants

The company stopped the trial early and plans to file for US approval by the end of 2022

There are currently no RSV vaccines approved for older adults anywhere worldwide

The vaccine demonstrated overall efficacy of 82.5% in adults aged 60 years and older

ZOSTER-049 follows participants from two phase 3 trials for an additional six years

A 30µg dose of the booster demonstrated a ‘substantial increase’ in antibody response

The constantly evolving nature of influenza viruses requires frequent reformulation of vaccines

Available vaccine strains that match circulating influenza viruses offer only 40%-60% protection

The company believes two key features of its patented mRNA technology platform were copied