
H3 K27M-mutant diffuse midline glioma affects an estimated 2,000 people in the US every year

Approximately 26% of biliary tract cancer patients globally have HER2-positive disease

Approximately 30,000 new cases of small cell lung cancer are reported in the US every year

Approximately 30,000 new cases of small cell lung cancer are reported in the US every year

Early study results published in peer-reviewed journal Science

Drug combination failed to improve overall survival rate

Collaboration will focus on two cancer targets on the Ras/Raf/MAP kinase pathway

Solidifies immunotherapy drug's dominance in the setting

Will go head-to-head with rival Roche's Tecentriq if approved

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Becomes the first checkpoint inhibitor for this indication