transthyretin amyloidosis with cardiomyopathy
Alnylam and Inceptive agree on $2bn AI collaboration
The deal will assist accelerate the discovery of RNAi therapeutics
Alnylam’s Amvuttra approved by MHRA to treat rare heart disease ATTR-CM
The drug has been authorised to treat both wild-type and hereditary forms of the disease
Alnylam’s Amvuttra granted EC approval to treat rare heart disease ATTR-CM
The RNAi therapeutic has been authorised to treat both wild type and hereditary forms of the disease
Alnylam shares phase 3 results for Amvuttra in rare heart disease ATTR-CM
Transthyretin amyloid cardiomyopathy is estimated to affect over 300,000 people worldwide
Alnylam’s RNAi therapeutic vutrisiran recommended by CHMP for rare heart disease
The committee has recommended the drug for both wild type and hereditary ATTR-CM
Alnylam’s Amvuttra granted FDA approval for rare heart disease ATTR-CM
Approximately 150,000 people in the US are affected by transthyretin amyloid cardiomyopathy
Alnylam shares positive phase 3 results for vutrisiran in ATTR with cardiomyopathy
The company said it will be proceeding with regulatory filings for the therapy later this year
Alnylam presents positive late-stage results for RNAi therapeutic in ATTR with cardiomyopathy
Hereditary ATTR and wild-type ATTR are responsible for an estimated 350,000 cases globally
Alnylam’s patisiran backed by FDA advisory committee for ATTR cardiomyopathy
Treatment options for the underdiagnosed and rapidly progressive condition are currently limited
Roche partners with Alnylam on hypertension therapy in deal worth up to $2.8bn
Zilebesiran is in phase 2 development to treat hypertension in patients with high-unmet needs
Alnylam presents promising results for RNAi therapeutic in Alzheimer’s disease at AAIC
ALN-APP is the first investigational RNAi therapeutic to show gene silencing in the human brain
Alnylam’s RNAi therapeutic recommended by NICE for hereditary form of amyloidosis
Amvuttra is given every three months, compared to every few weeks with existing therapies