| Drug Name | Company Name | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024(F) | 2025(F) | 2026(F) | 2027(F) | 2028(F) | 2029(F) | 2030(F) | 2023 Growth($M) | 2023 Growth(%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Botox Therapeutics | AbbVie Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $1,387 | $2,451 | $2,719 | $2,991 | $3,205 | $3,320 | $3,473 | $3,633 | $3,781 | $3,929 | $4,082 | $272 | 10.0% |
| Eylea 1 | Bayer AG | - | - | - | - | - | - | $18 | $442 | $1,008 | $1,363 | $1,798 | $2,120 | $2,578 | $2,792 | $2,814 | $3,451 | $3,378 | $3,494 | $3,431 | $3,201 | $2,647 | $2,223 | $1,810 | $1,532 | $1,261 | $116 | 3.4% |
| Pomalyst/Imnovid | Bristol-Myers Squibb Co | - | - | - | - | - | - | - | - | - | - | - | - | - | $322 | $3,070 | $3,332 | $3,497 | $3,441 | $3,429 | $3,102 | $1,348 | $581 | $257 | $164 | $116 | ($56) | -1.6% |
| Vyndaqel/Vyndamax | Pfizer Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | $473 | $1,288 | $2,015 | $2,447 | $3,321 | $5,052 | $6,075 | $6,492 | $6,267 | $5,967 | $2,835 | $1,938 | $874 | 35.7% |
| Tremfya | Johnson & Johnson | - | - | - | - | - | - | - | - | - | - | - | $63 | $544 | $1,012 | $1,347 | $2,127 | $2,668 | $3,147 | $3,697 | $4,541 | $5,443 | $6,271 | $7,057 | $7,767 | $8,437 | $479 | 18.0% |
| Soliris | AstraZeneca Plc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $1,874 | $3,762 | $3,145 | $2,704 | $2,120 | $1,622 | $1,259 | $986 | $789 | $612 | ($617) | -16.4% |
| Verzenio | Eli Lilly and Co | - | - | - | - | - | - | - | - | - | - | - | $21 | $255 | $580 | $913 | $1,350 | $2,484 | $3,863 | $5,196 | $6,233 | $7,107 | $7,743 | $8,163 | $8,472 | $8,784 | $1,379 | 55.5% |
| Ofev | Boehringer Ingelheim International GmbH | - | - | - | - | - | - | - | - | - | $397 | $678 | $964 | $1,298 | $1,669 | $2,343 | $2,946 | $3,393 | $3,796 | - | - | - | - | - | - | - | $403 | 11.9% |
| Enbrel | Amgen Inc | $2,879 | $3,230 | $3,598 | $3,493 | $3,534 | $3,701 | $4,236 | $4,551 | $4,688 | $5,364 | $5,965 | $5,433 | $5,014 | $5,226 | $4,996 | $4,465 | $4,117 | $3,697 | $3,304 | $3,034 | $2,724 | $2,520 | $2,310 | $1,831 | $1,425 | ($420) | -10.2% |
| Privigen | CSL Ltd | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $2,832 | $3,624 | - | - | - | - | - | - | - | $792 | 28.0% |
| Orencia | Bristol-Myers Squibb Co | $89 | $231 | $441 | $602 | $733 | $917 | $1,176 | $1,444 | $1,652 | $1,885 | $2,265 | $2,479 | $2,710 | $2,977 | $3,157 | $3,306 | $3,464 | $3,601 | $3,637 | $3,674 | $3,540 | $3,456 | $3,340 | $3,262 | $3,194 | $137 | 4.0% |
| Tecentriq | Roche Holding AG | - | - | - | - | - | - | - | - | - | - | $159 | $495 | $789 | $1,887 | $2,917 | $3,627 | $3,894 | $4,192 | $4,161 | $4,274 | $4,386 | $4,479 | $4,520 | $4,506 | $4,370 | $298 | 7.7% |
| Invega Sustenna/Xeplion /Trinza /Trevicta | Johnson & Johnson | - | - | - | - | - | $378 | $796 | $1,248 | $1,588 | $1,830 | $2,214 | $2,569 | $2,928 | $3,330 | $3,653 | $4,022 | $4,140 | $4,115 | $4,202 | $4,272 | $4,373 | $4,469 | $4,571 | $4,667 | $4,765 | ($25) | -0.6% |
| Prolia | Amgen Inc | - | - | - | - | $33 | $203 | $472 | $744 | $1,030 | $1,312 | $1,635 | $1,968 | $2,291 | $2,672 | $2,763 | $3,248 | $3,628 | $4,048 | $4,474 | $4,052 | $3,219 | $2,740 | $2,372 | $2,049 | $1,755 | $420 | 11.6% |
| Rinvoq | AbbVie Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | $47 | $731 | $1,651 | $2,522 | $3,969 | $5,741 | $7,420 | $8,997 | $10,310 | $11,425 | $12,323 | $13,172 | $1,447 | 57.4% |
| Perjeta | Roche Holding AG | - | - | - | - | - | - | $60 | $352 | $1,004 | $1,502 | $1,874 | $2,231 | $2,835 | $3,545 | $4,137 | $4,327 | $4,282 | $4,194 | $4,004 | $3,854 | $3,366 | $2,777 | $2,283 | $1,830 | $1,437 | ($88) | -2.1% |
| Wegovy | Novo Nordisk AS | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $220 | $875 | $4,550 | $8,476 | $13,267 | $16,683 | $18,303 | $18,987 | $19,266 | $19,404 | $3,675 | 420.0% |
| Gammagard | Takeda Pharmaceutical Co Ltd | - | - | - | - | - | - | - | - | - | - | - | - | $663 | $2,748 | $3,159 | $3,436 | $3,858 | $4,461 | $5,223 | $5,678 | $6,080 | $6,477 | $6,893 | $7,326 | $7,783 | $603 | 15.6% |
| Xarelto Sales and Royalty | Bayer AG | - | - | - | - | - | - | - | - | - | - | - | - | - | $4,619 | $5,147 | $5,599 | $4,749 | $4,413 | $3,957 | $3,320 | $2,212 | $1,286 | $1,012 | $852 | $595 | ($336) | -7.1% |
| Shingrix | GSK plc | - | - | - | - | - | - | - | - | - | - | - | $28 | $1,045 | $2,310 | $2,551 | $2,367 | $3,646 | $4,285 | $4,756 | $5,270 | $5,780 | $5,968 | $6,054 | $6,156 | $6,239 | $639 | 17.5% |
| Imfinzi/Imjudo | AstraZeneca Plc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $2,783 | $4,237 | - | - | - | - | - | - | - | $1,454 | 52.2% |
| Xtandi | Astellas Pharma Inc | - | - | - | - | - | - | $148 | $580 | $1,334 | $2,107 | $2,328 | $2,656 | $3,005 | $3,680 | $4,324 | $4,757 | $4,884 | $5,193 | $5,460 | $5,072 | $4,884 | $3,321 | $2,050 | $1,312 | $866 | $309 | 6.3% |
| Mounjaro | Eli Lilly and Co | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $483 | $5,163 | $11,823 | $17,368 | $22,067 | $25,532 | $28,631 | $30,668 | $32,439 | $4,680 | 968.9% |
| Cosentyx | Novartis AG | - | - | - | - | - | - | - | - | - | $261 | $1,128 | $2,071 | $2,837 | $3,551 | $3,995 | $4,718 | $4,788 | $4,980 | $6,007 | $6,568 | $7,025 | $7,404 | $7,650 | $7,324 | $6,163 | $192 | 4.0% |
| Ibrance | Pfizer Inc | - | - | - | - | - | - | - | - | - | $723 | $2,135 | $3,126 | $4,118 | $4,960 | $5,392 | $5,437 | $5,120 | $4,753 | $4,384 | $4,045 | $3,816 | $3,347 | $1,655 | $1,190 | $900 | ($367) | -7.2% |
| Hemlibra | Roche Holding AG | - | - | - | - | - | - | - | - | - | - | - | $3 | $229 | $1,389 | $2,334 | $3,306 | $4,005 | $4,616 | $4,914 | $5,227 | $5,461 | $5,596 | $5,636 | $5,677 | $5,581 | $611 | 15.3% |
| Entresto | Novartis AG | - | - | - | - | - | - | - | - | - | $21 | $170 | $507 | $1,028 | $1,726 | $2,497 | $3,548 | $4,644 | $6,035 | $7,894 | $7,937 | $6,017 | $4,507 | $2,690 | $1,626 | $1,009 | $1,391 | 30.0% |
| Forxiga | AstraZeneca Plc | - | - | - | - | - | - | - | - | - | $492 | $835 | $1,074 | $1,391 | $1,543 | $1,959 | $3,000 | $4,381 | $5,963 | $7,462 | $7,923 | $6,993 | $5,939 | $4,614 | $3,664 | $2,917 | $1,582 | 36.1% |
| Tagrisso | AstraZeneca Plc | - | - | - | - | - | - | - | - | - | $19 | $423 | $955 | $1,860 | $3,189 | $4,328 | $5,015 | $5,444 | $5,799 | $6,392 | $6,830 | $7,161 | $7,421 | $7,610 | $7,601 | $7,700 | $355 | 6.5% |
| Eylea | Regeneron Pharmaceuticals Inc | - | - | - | - | - | $25 | $838 | $1,409 | $1,736 | $2,676 | $3,323 | $3,702 | $4,077 | $4,644 | $4,947 | $5,792 | $6,265 | $5,720 | $4,657 | $3,500 | $2,470 | $1,520 | $937 | $585 | $384 | ($545) | -8.7% |
| Entyvio | Takeda Pharmaceutical Co Ltd | - | - | - | - | - | - | - | - | $270 | $721 | $1,322 | $1,816 | $2,428 | $3,194 | $4,049 | $4,645 | $5,191 | $5,542 | $6,499 | $7,062 | $7,464 | $7,740 | $7,984 | $8,182 | $8,410 | $351 | 6.8% |
| Trulicity | Eli Lilly and Co | - | - | - | - | - | - | - | - | $10 | $249 | $926 | $2,030 | $3,199 | $4,128 | $5,068 | $6,472 | $7,440 | $7,133 | $5,000 | $3,720 | $3,100 | $2,394 | $1,825 | $1,329 | $870 | ($307) | -4.1% |
| Ocrevus | Roche Holding AG | - | - | - | - | - | - | - | - | - | - | - | $883 | $2,405 | $3,732 | $4,609 | $5,531 | $6,323 | $7,103 | $7,594 | $8,053 | $8,411 | $8,618 | $8,520 | $8,141 | $7,785 | $780 | 12.3% |
| Spikevax | Moderna Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $200 | $17,675 | $18,435 | $6,671 | $2,922 | $2,647 | $2,679 | $2,660 | $2,697 | $2,663 | $2,626 | ($11,764) | -63.8% |
| Prevnar 13/Prevenar 13/Prevnar 20/Apexxnar | Pfizer Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $5,272 | $6,337 | $6,440 | $6,533 | $6,472 | $6,438 | $6,388 | $6,347 | $6,315 | $6,292 | $103 | 1.6% |
| Revlimid | Bristol-Myers Squibb Co | - | - | - | - | - | - | - | - | - | - | - | - | - | $1,299 | $12,106 | $12,821 | $9,978 | $6,097 | $4,788 | $2,553 | $852 | $480 | $268 | $208 | $155 | ($3,881) | -38.9% |
| Opdivo | Bristol-Myers Squibb Co | - | - | - | - | - | - | - | - | $6 | $942 | $3,774 | $4,948 | $6,735 | $7,204 | $6,992 | $7,523 | $8,249 | $9,009 | $9,789 | $10,415 | $10,948 | $11,398 | $11,411 | $9,751 | $8,099 | $760 | 9.2% |
| Trikafta/Kaftrio | Vertex Pharmaceuticals Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | $420 | $3,864 | $5,697 | $7,687 | $8,945 | $8,950 | $10,438 | $10,613 | $10,762 | $10,749 | $10,788 | $11,031 | $1,258 | 16.4% |
| Gardasil/ Gardasil 9 | Merck & Co Inc | $235 | $1,481 | $1,403 | $1,118 | $988 | $1,209 | $1,631 | $1,831 | $1,738 | $1,908 | $2,173 | $2,308 | $3,151 | $3,737 | $3,938 | $5,673 | $6,897 | $8,886 | $9,618 | $10,202 | $10,756 | $11,139 | $11,437 | $11,688 | $11,902 | $1,989 | 28.8% |
| Jardiance | Boehringer Ingelheim International GmbH | - | - | - | - | - | - | - | - | - | - | - | $1,136 | $1,724 | $2,409 | $2,827 | $4,659 | $6,132 | $7,983 | - | - | - | - | - | - | - | $1,851 | 30.2% |
| Skyrizi | AbbVie Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | $355 | $1,590 | $2,939 | $5,165 | $7,763 | $10,981 | $13,785 | $16,195 | $17,979 | $19,487 | $20,645 | $21,676 | $2,598 | 50.3% |
| Biktarvy | Gilead Sciences Inc | - | - | - | - | - | - | - | - | - | - | - | - | $1,184 | $4,738 | $7,259 | $8,624 | $10,390 | $11,850 | $12,940 | $13,605 | $14,112 | $14,427 | $14,640 | $14,953 | $15,234 | $1,460 | 14.1% |
| Dupixent | Sanofi | - | - | - | - | - | - | - | - | - | - | - | $247 | $930 | $2,322 | $4,029 | $6,207 | $8,720 | $11,588 | $14,127 | $16,465 | $18,341 | $19,944 | $21,299 | $22,523 | $23,582 | $2,868 | 32.9% |
| Comirnaty | Pfizer Inc | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $154 | $36,781 | $37,806 | $11,220 | $5,082 | $4,631 | $4,234 | $4,010 | $3,768 | $3,675 | $3,673 | ($26,586) | -70.3% |
| Stelara | Johnson & Johnson | - | - | - | - | $393 | $738 | $1,025 | $1,504 | $2,072 | $2,474 | $3,232 | $4,011 | $5,156 | $6,361 | $7,707 | $9,134 | $9,723 | $10,858 | $10,005 | $7,103 | $5,153 | $3,675 | $2,470 | $1,626 | $1,198 | $1,135 | 11.7% |
| Darzalex/Faspro | Johnson & Johnson | - | - | - | - | - | - | - | - | - | - | - | - | - | - | $4,190 | $6,023 | $7,977 | $9,744 | $11,510 | $13,277 | $15,076 | $16,789 | $18,308 | $19,799 | $20,095 | $1,767 | 22.2% |
| Eliquis | Bristol-Myers Squibb Co | - | - | - | - | - | - | $2 | $146 | $774 | $1,860 | $3,343 | $4,872 | $6,438 | $7,929 | $9,168 | $10,762 | $11,789 | $12,206 | $13,351 | $13,898 | $12,207 | $11,056 | $6,574 | $3,101 | $1,944 | $417 | 3.5% |
| Keytruda | Merck & Co Inc | - | - | - | - | - | - | - | - | $55 | $566 | $1,402 | $3,809 | $7,171 | $11,084 | $14,380 | $17,186 | $20,937 | $25,011 | $28,645 | $31,037 | $32,945 | $34,300 | $33,662 | $27,567 | $23,187 | $4,074 | 19.5% |
| Humira | AbbVie Inc | - | - | - | - | - | - | - | $10,659 | $12,543 | $14,012 | $16,078 | $18,427 | $19,936 | $19,169 | $19,832 | $20,694 | $21,237 | $14,404 | $9,599 | $6,920 | $5,386 | $4,357 | $3,578 | $2,938 | $2,324 | ($6,833) | -32.2% |
| Ozempic | Novo Nordisk AS | - | - | - | - | - | - | - | - | - | - | - | - | $284 | $1,685 | $3,244 | $5,360 | $8,446 | $13,894 | $17,933 | $20,851 | $23,498 | $23,272 | $23,648 | $23,666 | $23,443 | $5,448 | 64.5% |
Top 50 products based on 2023 Global sales
The ranking of the top pharmaceutical companies has been compiled from GlobalData’s pharmaceutical revenue figures, which are based on sales of prescription medicines, including generics drugs. The rankings include historical data from 2006 to 2023 and forecast data for 2024 to 2030.
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For more details on the data and methodology used to create the Top Pharma Lists, please visit PMLiVE’s Top Pharma List – Methodology